At ZP, we receive inquiries about wearable creatinine sensors for dialysis patients, often exploring copper ions for detection. While copper-based sensing can work at early technology readiness levels, regulatory concerns about introducing copper into the bloodstream should be considered. An enzyme-based system, though more complex, could offer an alternative. Wearable creatinine sensing is challenging due to multiple enzymatic steps, making glucose sensors a simpler starting point. Companies like Biolink have raised substantial funding for similar technology. If you have technical questions, feel free to reach out—we’re always happy to share insights!